MORPHOFUNCTIONAL FEATURES OF MICROCIRCULATORY BED ALTERATIONS IN PATHOLOGICAL CONDITIONS BASED ON HISTOLOGICAL ANALYSIS
Keywords:
Microcirculation, histology, endothelial dysfunction, capillaries, pathological conditions, tissue hypoxiaAbstract
The microcirculatory bed plays a critical role in maintaining tissue homeostasis by обеспечивая adequate oxygen delivery, nutrient exchange, and metabolic waste removal. In pathological conditions, disturbances of microcirculation represent an early and fundamental mechanism of tissue injury. This article aims to analyze the morphofunctional features of microcirculatory bed alterations in various pathological conditions based on histological examination. The findings reveal that endothelial damage, capillary dilation, microthrombosis, and increased vascular permeability are key histological features associated with impaired tissue perfusion and progressive organ dysfunction. Understanding these changes has significant diagnostic and clinical importance.
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