FEATURES OF BACTERIOPHAGE APPLICATION IN THE THERAPY OF INFECTIONS CAUSED BY OPPORTUNISTIC STRAINS OF KLEBSIELLA PNEUMONIAE

Solomonnik Oksana Nikolaevna‌‌

Authors

Solomonnik Oksana Nikolaevna‌‌ Department of infectious diseases Andijan State Medical Institute,Uzbekistan, Andijan

Keywords:

Klebsiella pneumoniae, Bacteriophage, Antibiotic resistance, Phage therapy, Opportunistic microorganisms, Respiratory tract infections, Immunity

Abstract

In the context of the rapid rise of antimicrobial resistance among microbial pathogens, the need for alternative methods of treating bacterial infections has become increasingly evident. Klebsiella pneumoniae is one of the opportunistic pathogens that, under certain conditions (immunosuppression, chronic diseases, etc.), can cause severe forms of pneumonia, urinary tract infections, sepsis, and other pathological conditions. Conventional antibiotic therapy against resistant K. pneumoniae strains often proves insufficiently effective or is associated with significant side effects. In this situation, the use of bacteriophages appears to be a promising approach, as bacteriophages have the ability to selectively target and destroy bacterial cells without disrupting the body’s normal microflora.

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