AGE-RELATED PATHOMORPHOLOGICAL CHANGES OF DYSREGENERATIVE PROCESSES IN NON-SPECIFIC ULCERATIVE COLITIS
Keywords:
Morphology, enteric nervous system, neurons, colitis, glia.Abstract
A morphological study of the enteric nervous system of the colon was carried out in C57Bl/6 mice with experimental dextran-induced acute ulcerative colitis. The cellular composition of the myenteric ganglia and cytometric parameters of myenteric neurons were studied. In colitis, compared with the control, a decrease in the number of hypochromic neurons and gliocytes, an increase in the number of hyperchromic neurons per ganglion, and a decrease in the size of neurons and their nuclei were revealed.
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