APPLICATION OF AUTOLOGOUS PRF MEMBRANES IN SURGICAL TREATMENT OF ZYGOMATIC-ORBITAL COMPLEX INJURIES

Shokhrukh Yusupov,Shukhrat Boymuradov,Komiljon Iminov

Authors

Shokhrukh Yusupov,Shukhrat Boymuradov,Komiljon Iminov DSc, Associate Professor,DSc, Professor Department of Maxillofacial Surgery, Tashkent State Medical University, Tashkent, Uzbekistan

Keywords:

Zygomatic-orbital complex fractures are among the most complex injuries of the facial skeleton due to the anatomical and functional importance of the midfacial region.

Abstract

Background:

Zygomatic-orbital complex injuries are frequently associated with severe damage to bone and soft tissue structures of the midface, resulting in functional and aesthetic impairment. Modern craniofacial surgery increasingly focuses not only on anatomical reconstruction but also on optimization of tissue healing and postoperative rehabilitation. Platelet-rich fibrin (PRF) represents an autologous biological material containing growth factors that may enhance tissue regeneration and reduce postoperative complications.

Objective:

To evaluate the effectiveness of autologous PRF membranes in surgical treatment and postoperative rehabilitation of patients with zygomatic-orbital complex injuries.

Materials and Methods

A clinical study included patients with zygomatic-orbital complex fractures who underwent surgical treatment with open reduction and internal fixation. In the study group, autologous PRF membranes were applied intraoperatively in the region of osteosynthesis and orbital reconstruction. Clinical, radiological, and anthropometric evaluation was performed preoperatively and postoperatively. Functional outcomes, soft tissue healing, postoperative edema, pain intensity, and complication rates were analyzed.

Results:

Application of PRF membranes demonstrated improved postoperative soft tissue healing, reduction of edema, decreased pain intensity, and accelerated rehabilitation. Patients treated with PRF showed favorable regeneration of soft tissues surrounding the orbital region and osteosynthesis sites. Anthropometric analysis demonstrated improved restoration of facial symmetry and midfacial contour. No adverse reactions related to PRF application were observed.

Conclusion:

Autologous PRF membranes represent a safe and effective adjunctive method in surgical treatment of zygomatic-orbital complex injuries. PRF application contributes to enhanced tissue regeneration, reduction of postoperative inflammatory response, and improvement of functional and aesthetic outcomes.

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