MORPHOLOGICAL PREDICTORS OF VASCULAR COMPLICATIONS IN METABOLIC SYNDROME: AN ANATOMICAL PERSPECTIVE

Fayzullayev Farrux Murodullo ugli,Abdusamadov Mukhammad Abdimurod ugli,Tursunov kho'janbek Chori ugli,Eshqovulov Og‘abek Khusan ugli , Begimova Mehriniso Mengli kizi

Authors

Fayzullayev Farrux Murodullo ugli,Abdusamadov Mukhammad Abdimurod ugli,Tursunov kho'janbek Chori ugli,Eshqovulov Og‘abek Khusan ugli , Begimova Mehriniso Mengli kizi Student, Termez Branch of Tashkent State Medical University.,Student, Termez Branch of Tashkent State Medical University.,Student, Termez Branch of Tashkent State Medical University.,Student, Termez Branch of Tashkent State Medical University.,Senior Lecturer, Department of Anatomy, Termez Branch of Tashkent State Medical University.

Keywords:

metabolic syndrome, vascular complications, morphology, endothelium, intima, atherosclerosis, vascular remodeling, anatomical predictors, histopathology, cardiovascular risk, endothelial dysfunction, arterial wall

Abstract

Metabolic syndrome is a multifactorial condition characterized by a cluster of metabolic abnormalities, including insulin resistance, central obesity, dyslipidemia, and hypertension, all of which significantly increase the risk of cardiovascular diseases. This article aims to analyze morphological predictors of vascular complications in patients with metabolic syndrome from an anatomical and histopathological perspective. Special attention is given to structural alterations in blood vessels, including endothelial dysfunction, intimal thickening, and vascular remodeling. The study integrates current anatomical knowledge with clinical and experimental findings to identify key predictors of vascular damage. Understanding these morphological changes is essential for early diagnosis, risk stratification, and the development of preventive strategies in modern medicine.