Interdisciplinary Integration of Genomic Evolution, Nanotechnology, And Phytochemical Interventions: Evaluating Pomegranate Peel Extract in Zebrafish Models And Aquaculture Sustainability

Sara Khan

Authors

Sara Khan Institute of Biological Sciences, University of Edinburgh, United Kingdom

Keywords:

Zebrafish, Pomegranate Peel Extract, Green Nanotechnology, Aquaculture

Abstract

The intersection of genomic science, green nanotechnology, and sustainable aquaculture represents a burgeoning frontier in modern biotechnology. This comprehensive research article investigates the multifaceted applications of Pomegranate Peel Extract (PPE) and synthesized metallic nanoparticles within the zebrafish (Danio rerio) model system, while contextualizing these findings within the broader framework of fish physiology, stress management, and genomic evolution. By synthesizing data from green synthesis of silver and copper nanoparticles to the neurobehavioral impacts of PPE, this study elucidates how secondary metabolites from agricultural waste can mitigate oxidative stress and serve as therapeutic agents. Furthermore, the article explores the genomic underpinnings of adaptive evolution in teleosts, such as the zebrafish and Atlantic cod, to understand the heritage of physiological resilience. Through extensive theoretical elaboration, the research demonstrates that PPE-mediated nano-antioxidants offer a superior alternative to synthetic additives in aquaculture, promoting both fish health and environmental sustainability. The study concludes that an integrated approach-combining molecular docking, deep learning for pharmacokinetic prediction, and in vivo neurobehavioral assessment-is essential for the next generation of pharmacological interventions in aquatic systems.

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