THE EFFECT OF HYPERANDROGENISM AND POLYCYSTIC OVARY SYNDROME (PCOS) ON PREGNANCY

Authors

  • Davronova Dilshoda Mansurjon qizi, Zufarova Shakhnoza Alimjanovna Tashkent Medical University

Keywords:

hyperandrogenism, PCOS, pregnancy, infertility, insulin resistance, ovulation, spontaneous abortion.

Abstract

The purpose of this article is to analyze the effect of hyperandrogenism on pregnancy in women with polycystic ovary syndrome (PCOS) based on modern scientific sources. Based on international clinical guidelines, the impact of hyperandrogenism on ovulation, implantation, spontaneous abortion, and live birth rates was analyzed. The study presents a theoretical analytical review that summarizes available scientific evidence and provides final conclusions regarding the relationship between hyperandrogenism and reproductive outcomes in women with PCOS.

References

Azziz, R., Carmina, E., Chen, Z., et al. (2016). Polycystic ovary syndrome. Nature Reviews Disease Primers, 2, 16057.

https://doi.org/10.1038/nrdp.2016.57

Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. (2004). Revised 2003 consensus on diagnostic criteria and long-term health risks related to PCOS. Human Reproduction, 19(1), 41–47.

https://doi.org/10.1093/humrep/deh098

Franks, S. (2008). Polycystic ovary syndrome in adolescents. The New England Journal of Medicine, 359, 1435–1446.

https://doi.org/10.1056/NEJMra070431

Dunaif, A. (1997). Insulin resistance and the polycystic ovary syndrome. Endocrine Reviews, 18(6), 774–800.

https://doi.org/10.1210/edrv.18.6.0318

Palomba, S., et al. (2015). Pregnancy complications in women with PCOS. Human Reproduction Update, 21(5), 575–592.

https://doi.org/10.1093/humupd/dmv029

Legro, R. S., et al. (2014). Letrozole versus clomiphene for infertility in PCOS. The New England Journal of Medicine, 371, 119–129.

https://doi.org/10.1056/NEJMoa1313517

Boomsma, C. M., et al. (2006). Pregnancy complications in women with PCOS: a meta-analysis. Human Reproduction Update, 12(6), 673–683.

https://doi.org/10.1093/humupd/dml036

Tang, T., Lord, J. M., Norman, R. J., et al. (2012). Metformin for women with PCOS undergoing assisted reproduction. Human Reproduction Update, 18(2), 191–201.

https://doi.org/10.1093/humupd/dmr056

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Published

2026-03-07

How to Cite

Davronova Dilshoda Mansurjon qizi, Zufarova Shakhnoza Alimjanovna. (2026). THE EFFECT OF HYPERANDROGENISM AND POLYCYSTIC OVARY SYNDROME (PCOS) ON PREGNANCY. Ethiopian International Journal of Multidisciplinary Research, 13(03), 18–21. Retrieved from https://eijmr.org/index.php/eijmr/article/view/5450