THE IMPORTANCE OF CT ANGIOGRAPHY AND ECHOCARDIOGRAPHY IN THE EARLY DETECTION OF SUDDEN PULMONARY EMBOLISM IN CHRONIC HEART FAILURE.
Keywords:
Pulmonary artery thromboembolism, streptokinase, hypoxic thrombolysis, early diagnosis, D-dimer, CT angiography, hypoxemia, right heart failure, revascularization.Abstract
Pulmonary artery thromboembolism (PATE) is an acute pathological condition resulting from the occlusion of the pulmonary artery by thrombus masses, which leads to serious morphological changes. This article reviews the etiology and pathogenesis of PATE, morphological changes in lung tissue, and their use in diagnosis. The role and significance of diagnostic tests, as well as the effectiveness of various therapeutic approaches, are also discussed through a comparison of various studies and experimental results. Pulmonary thromboembolism (PTE) is an urgent pathology with a high mortality rate and requires prompt diagnosis. Early detection of the disease and proper treatment significantly reduce the risk of death and complications. Computed tomography angiography (CT angiography) is currently considered the “gold standard” for the diagnosis of PTE. This article reviews the diagnostic capabilities of CT angiography, its sensitivity and specificity, and the impact of contrast media on the diagnosis of PTE.
The results of the study demonstrate the high efficiency of CT angiography in detecting small and segmental thromboemboli at an early stage. It is also justified that additional assessment of perfusion disorders is important in clinical decision-making. The obtained data confirm that early detection of pulmonary embolism using CT angiography is the most optimal and reliable method in clinical practice.
References
Konstantinides SV, Meyer G, Becattini C, et al. 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism. Eur Heart J. 2020;41(4):543– 603.
Jaff MR, McMurtry MS, Archer SL, et al. Management of massive and submassive pulmonary embolism. Circulation. 2011;123(16):1788–1830.
Meyer G, Vicaut E, Danays T, et al. Fibrinolysis for patients with intermediate -risk pulmonary embolism. N Engl J Med. 2014;370(15):1402–1411.
Goldhaber SZ, Visani L, De Rosa M. Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER). Lancet. 1999;353(9162):1386–1389.
Piazza G, Goldhaber SZ. Management of submassive pulmonary embolism. Circulation. 2010;122(11):1124–1129.
Kucher N, Rossi E, De Rosa M, Goldhaber SZ. Massive pulmonary embolism. Circulation. 2006;113(4):577–582.
Tapson VF. Acute pulmonary embolism. N Engl J Med. 2008;358(10):1037–1052.
Windecker S, Kolh P, Alfonso F, et al. ESC/EACTS Guidelines on myocardial revascularization. Eur Heart J. 2014;35(37):2541–2619.






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