SYNTHESIS OF THIOETHERS BASED ON THIOL-EN AND THIOL-IN COMPOUNDATION REACTIONS
Keywords:
thiols, sulfur compounds, synthesis, thioethers, reactivity, biological activityAbstract
This article focuses on the synthesis of sulfur-containing organic compounds based on thiol-en and thiol-in addition reactions, their physicochemical properties, international scientific research, as well as their applications in industry, pharmaceuticals, and agriculture. In particular, the reactivity and importance of thiols, thioethers, sulfides, and sulfonic compounds in their applications are highlighted. At the same time, it serves as an important scientific-theoretical and practical basis for the further development of the synthesis of organic sulfur compounds and the development of environmentally friendly and effective technologies. The theoretical and practical results of the research lay the foundation for the further development of the chemistry of sulfur-containing organic compounds, the development and practical application of methods for the synthesis of new sulfur-containing compounds.
References
Block E. Garlic and other Alliums: the Lore and the Science. – Cambridge: Royal Society of chemistry, 2010. – 454 b
Г.З. Гусейнов, А.Г. Гасанов, Ф.С. Гурбанова Изучание реакции взаимодействия меркаптанов с непределъными соединениями Известия ТулГУ. Естественные науки. 2023. Вып. 3 DOI: 10.24412/2071-6176-2023-3-30-42
M. Nolan, A. Mezetta, L. Guazzelli [et al.] Radical-mediated thiol-ene ‘click’ reactions in deep eutectic solvents for bioconjugation // Green Chemistry. 2022. V. 24. N. 4. P. 1456–1462.
Taniguchi N.Zinc-Catalyzed Regioselective Addition of Alkyl Thiols
to Alkenes via Anion or Radical Reactions //ARKIVOC. 2021.N3.P.125
Taniguchi N. Bronsted Acid-Assisted Zinc-Catalyzed MarkovnikovType Hydrothiolation of Alkenes Using Thiols // Journal of Organic Chemistry.
V.40.N.3.P.467–472.
Kanagasabapathy S., Sudaini A., Benicewicz B. Montmorillonite K
Catalyzed Regioselective Addition of Thiols and Thiobenzoic Acids onto
Olefins: An Efficient Synthesis of Dithiocarboxylic Esters // Tetrahedron
Letters. 2001. V. 42. N. 23. P. 3791–3794.
Hoyle, C. E.; Bowman, C. N. Thiol-ene Click Chemistry: A Multifaceted Toolbox for Materials Design. Anegev. Chem. Int. Ed., 2010, 49, 1540-1573 DOI: 10.1002/anie.200903924
Lowe, A. B. Thiol–ene "click" reactions and recent applications in polymer and materials synthesis. Polym. Chem., 2010, 1, 17–36. DOI: 10.1039/B9PY00216B
Fairbanks, B. D., et al. Photoinitiated Polymerization of Thiol–Ene Systems. Macromolecules, 2009, 42, 211–217.
Cramer, N. B.; Bowman, C. N. Kinetic analysis of thiol–ene and thiol–yne photopolymerizations. Macromolecules, 2001, 34, 8875–8882.
Belley M., Zamboni R. Addition of thiols to styrenes. Formation of
benzylic thioethers. J. Org. Chem. 1989. V. 54. N. 5. P. 1230–1232.
Ranu B.C., Mandal T. Water-Promoted Highly Selective AntiMarkovnikov Addition of Thiols to Unactivated Alkenes // Synlett. 2007. N. 2.
P. 925–928.






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