THE RELEVANCE OF DEVELOPING KELOID SCARS AFTER DIAGNOSIS AND THE SCIENTIFIC BASIS OF TREATMENT METHODS

Abstract

This article analyzes the clinical significance, pathogenesis, and scientifically grounded treatment methods of keloid scars that develop after surgical interventions. Keloids are characterized by fibroblast hyperactivity, excessive collagen production, and impaired skin regeneration, which result in a high recurrence rate and significant cosmetic, functional, and psycho-emotional consequences. The study evaluates various therapeutic approaches, including surgical excision, corticosteroid therapy, laser techniques, cryotherapy, radiotherapy, silicone-based treatments, and lymphatic therapy. Clinical observations from 2021 to 2025 at the Andijan State Medical Institute demonstrate that a combined approach—particularly surgical excision followed by desensitization, regional lymphatic therapy, antihistamines, and topical Contractubex—significantly reduces the risk of recurrence. The findings support a comprehensive and pathogenetically oriented strategy as the most effective way to prevent postoperative keloid recurrence.