PREVENTION AND MANAGEMENT OF POSTOPERATIVE INFECTIONS: RATIONAL MODELS OF ANTIBIOTIC THERAPY
Keywords:
Postoperative infections, surgical site infection, antibiotic therapy, antibiotic prophylaxis, rational models, bacterial resistance, perioperative prevention.Abstract
Postoperative infections (POIs) remain one of the most urgent complications in surgical practice and significantly influence morbidity, mortality, length of hospital stay and treatment costs. In recent years, the rational use of antibiotic prophylaxis and therapy has been considered the main strategy to prevent bacterial resistance and achieve effective clinical outcomes. This article analyzes modern approaches to prevention and management of postoperative infections, focusing on evidence-based antibiotic therapy, risk factor identification, and optimization of perioperative prevention. The article also provides research methods, results, and practical conclusions on forming rational therapeutic models.
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