HEMATOLOGICAL INDICATORS IN DISORDER OF PLACENTERAL BLOOD CIRCULATION AND PREDICTION OF PERINATAL COMPLICATIONS
Keywords:
placental insufficiency; perinatal complications; hemoglobin; platelets; fibrinogen; D-dimer; prognostic scale; ROC analysis; fetal hypoxia.Abstract
The study assesses the relationship between hematological indicators of pregnant women with uteroplacental blood flow disorders, placental morphology, and perinatal outcomes. Anemia (Hb↓), tendency to thrombocytopenia (PLT↓), hyperfibrinogenemia and D-dimer elevation are indicated; Hb and PLT have a negative correlation with the total placental injury score, while D-dimer has a positive correlation. An integral prognostic scale (Hb, PLT, fibrinogen ± morphological index/CD95) with AUC 0.88 has been developed; sensitivity is 85%, specificity is 78% for predicting adverse perinatal outcomes.References
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