ANALYSIS OF THE FLAVONOID CONTENT IN THE COMPOSITION OF THE “GEPAGAL” MIXTURE

Abstract

 In this article, the flavonoid composition and quantitative indicators of the “Gepagal” substance, prepared from locally sourced medicinal plant raw materials, were thoroughly analyzed. During the research, the aim was to determine the content of the main bioactive compounds present in the substance — namely rutin, quercetin, dihydroquercetin, sennoside, and luteolin. For this purpose, the High-Performance Liquid Chromatography (HPLC) method was employed, which is distinguished by its accuracy, sensitivity, and reliability in analytical studies. The experimental results showed that each of the identified flavonoids was present in a measurable amount within the “Gepagal” substance; however, the luteolin content was found to be considerably higher compared to the other flavonoids. This finding indicates that luteolin serves as one of the principal active components of the preparation and plays a significant role in determining its biological activity and pharmacological effects. Furthermore, the obtained results are of great importance for improving the quality of pharmaceuticals derived from local medicinal plant materials and for scientifically substantiating their standardization process, thereby contributing to the development of effective and safe plant-based medicines.