STUDY OF THE SYNERGISTIC EFFECTS OF PLANT EXTRACTS AGAINST DIABETES
Keywords:
Diabetes, plant extract, synergism, antihyperglycemic activity, natural remedies, enzyme inhibition, phytotherapy, bioactive compounds, metabolic syndrome, glucose tolerance, polyphenols, phytocomplex, phytochemical analysis, phenolic compounds, alkaloids, terpenoids, insulin secretion, experimental model, biologically active supplement, pharmacological activity, phytopreparation development, natural-source therapy.Abstract
This scientific study examines the antidiabetic effects of bioactive extracts derived from various medicinal plants and explores their mutual synergistic (enhancing) interactions.
The aim of the research is to determine the potential for developing a safe and effective phytocomplex with hypoglycemic activity based on natural sources. The selected plants—Momordica charantia (bitter melon), Glycyrrhiza glabra (licorice root), and Brassica nigra (black mustard seeds)—are commonly used in traditional medicine for diabetes treatment. Their chemical composition was analyzed using chromatographic techniques (HPLC, GC–MS), and their ability to inhibit α-glucosidase enzymes was evaluated in vitro.
The results show that mixtures of plant extracts possess stronger antihyperglycemic activity than individual components, confirming their synergistic effect. These findings provide a valuable scientific basis for developing new combination-based plant-derived antidiabetic preparations.
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