PATHOGENESIS OF INCREASED INTRACRANIAL PRESSURE IN TRAUMATIC BRAIN INJURY

Baybekova G.J.

Authors

Baybekova G.J. Andijan State Medical Institute, Uzbekistan

Keywords:

traumatic brain injury, intracranial pressure, cerebral edema, autoregulation, ischemia, brain swelling

Abstract

Traumatic brain injury (TBI) remains one of the leading causes of morbidity and mortality worldwide, with increased intracranial pressure (ICP) being a key determinant of patient outcome. The elevation of ICP following head trauma results from a complex interplay of vascular, cellular, and biochemical mechanisms. This study analyzes the pathogenesis of raised ICP in TBI, emphasizing the role of cerebral edema, intracranial hemorrhage, impaired autoregulation, and secondary ischemic injury. Understanding these mechanisms is critical for effective monitoring and therapeutic intervention aimed at preserving cerebral perfusion and preventing herniation syndromes.

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