CLINICAL ASPECTS OF ENDOGENOUS INTOXICATION IN VIRAL HEPATITIS C
Keywords:
Viral hepatitis C (HCV), Endogenous intoxication, Hepatocellular damage, Inflammatory markers, Liver function, Cytokines, Oxidative stressAbstract
Viral hepatitis C (HCV) remains a critical global health challenge, affecting over 58 million people worldwide according to recent WHO estimates. Chronic hepatitis C is often asymptomatic in its early stages but can progress to cirrhosis and hepatocellular carcinoma if left untreated. One of the key pathophysiological features is the phenomenon of endogenous intoxication — the accumulation of toxic metabolites resulting from impaired liver function and ongoing inflammatory processes. Monitoring and managing endogenous intoxication in HCV patients is essential for slowing disease progression, improving quality of life, and ultimately reducing the overall burden of chronic liver disease.
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