PRODUCTION OF HORMONES DURING SLEEP

Osbayov Muhammadjon Imaralievich,Mamajonova Jasmina Akmaljon qizi

Authors

Osbayov Muhammadjon Imaralievich,Mamajonova Jasmina Akmaljon qizi Fergana Medical Institute of Public Health, Fergana city, Uzbekistan

Keywords:

Hormones, sleep, endocrine system, circadian rhythm, melatonin, growth hormone, cortisol, leptin, REM sleep, deep sleep.

Abstract

Sleep plays a crucial role in regulating the body's hormonal balance, influencing a variety of physiological processes, including growth, metabolism, stress response, and reproductive health. During different sleep stages, the body produces key hormones such as melatonin, growth hormone, cortisol, and leptin, each of which performs distinct functions that contribute to overall health and well-being. This article explores the mechanisms of hormone production during sleep, highlighting the interplay between the endocrine system and circadian rhythm. Understanding these processes can provide valuable insights into the impact of sleep quality and duration on hormonal health, potential implications for managing sleep-related disorders, and endocrine imbalances.

References

Leproult, R. and Van Cauter, E. (2010). The role of sleep and sleep deprivation in hormonal production and metabolism. Endocrine Development, 17, 11–21. https://doi.org/10.1159/000262524

Laposky, A.D., Bass, J., Kohsaka, A. , & Turek, F.W. (2008). Sleep and circadian rhythms: key components of energy metabolism regulation. FEBS Letters, 582(1), 142–151. https://doi.org/10.1016/j.febslet.2007.11.069

Spiegel, K., Tasali, E., Penev, P., & Van Cauter, E. (2004). Sleep deprivation in healthy young men is associated with decreased leptin levels, increased ghrelin levels, and increased hunger and appetite. Annals of Internal Medicine, 141(11), 846–850. https://doi.org/10.7326/0003-4819-141-11-200412070-00008

Brzezinski, A. (1997). Melatonin in humans. New England Journal of Medicine, 336 (3), 186–195. https://doi.org/10.1056/NEJM199701163360306

Buckley, TM and Schatzberg, AF (2005). On the interaction between the hypothalamic-pituitary-adrenal (HPA) axis and sleep: Normal HPA axis activity and circadian rhythm, a model of sleep disorders. Journal of Clinical Endocrinology and Metabolism, 90(5), 3106–3114. https://doi.org/10.1210/jc.2004-1056

Zee, PC and Manthena, P. (2007). The brain’s master circadian clock: implications and opportunities for the treatment of sleep disorders. Sleep Medicine Reviews, 11(1), 59–70. https://doi.org/10.1016/j.smrv.2006.07.001

Walker, MP (2009). The role of sleep in cognition and emotion. Proceedings of the New York Academy of Sciences, 1156, 168–197. https://doi.org/10.1111/j.1749-6632.2009.04416.x

Khabibullaev F., Osbaev M.U., Mamatkulova M.T. Features of the immune system of the mucous membrane of the small intestine, Intern. scientific. Conf. Actual Scientific Research in the Modern World, Issue 4 (24), Part 6, April 2017. p-137-141.

Imaraliyevich O.M. (2021). Features of the immune system structure of the mucosa of the small intestine of mice. Academicia Globe: Inderscience Research, 2(05). – PP. 42–46.

Осбаев М. Влияние растения алоэ на активность печени //Общество и инновации. – 2021. – Т. 2. – №. 4/S. – С. 885-889.