COMPREHENSIVE USE OF ANTIBACTERIAL DRUGS IN ACUTE AND CHRONIC INFECTIONS

Tukhtanazarova Nargiza Saiyibovna

Authors

Tukhtanazarova Nargiza Saiyibovna Department of infectious diseases, Andijan state medical institute

Keywords:

antibacterial therapy, combination antibiotic regimens, acute infections, chronic infections, antibiotic resistance, multidrug-resistant organisms, antimicrobial stewardship, clinical outcomes, microbiological eradication, treatment optimization

Abstract

This article discusses the rationale, strategies, and clinical outcomes of comprehensive antibacterial drug regimens in the management of acute and chronic infections. We present an overview of the most common pathogens, mechanisms of antibiotic resistance, and the principles of combination therapy and antibiotic stewardship. The results of a retrospective and a pilot prospective study underscore the potential benefits of carefully selected combination antimicrobial therapy, especially for infections complicated by multidrug-resistant organisms. These findings may guide clinicians and researchers in optimizing treatment protocols and improving patient outcomes.

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