EVIDENCE-BASED TECHNOLOGY TO DETERMINE THE IMMUNE RESPONSE TO THE EPIDEMIC OF CORONAVIRUS INFECTION

Yuldasheva Sarvinoza

Authors

Yuldasheva Sarvinoza Department of Faculty therapy, Andijan State Medical Institute,Andijan, Uzbekistan.

Keywords:

lymphocyte subpopulations, rheumatoid arthritis, SARS-CoV-2 infection, inflammation.

Abstract

Aim: The determination of lymphocyte subpopulations in patients with rheumatoid arthritis using the CD antigen markers, including CD3, CD4, CD8, CD16, CD20, CD25 and CD95. Materials and methods: Was examined 60 people aged 30-65 years were divided into the following 3 main groups: I group: 20 participants (16 female and 4 male) with RA , II group: of 20 individuals (14 female and 6 male) who had previously been diagnosed with SARS-CoV-2 infection, III group: control healthy participants20 healthy volunteers (15 female and 5 male).Results: This finding suggests that CD3+, CD4+, CD8+, CD16+ and CD20+ T-lymphocytes are the predominant CD25-producing cells and affect the content of this molecule not by altering the expression density of the CD25 receptor on their surface, but rather due to the increased number of these cells. Conclusion: The study of T lymphocyte subpopulations, which we have traced in our research, makes it possible to diagnose inflammation in an early stage and serves as an effective tool in primitive medicine.

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