COGNITIVE FUNCTIONS IN PATIENTS WITH CHRONIC MIGRAINE

Abstract

Migraine is the second most common form of headache, which affects 11-15% of the adult population [1, 2]. The prevalence of migraine in the adult population in Europe is 14% [3], in China – 9.3% [4], in the USA – 20.2% [5], in Russia – 20.3% [6]. Migraine is one of the most common forms of headache in Uzbekistan. According to research, about 8.1% of the population suffers from migraines, and most often this disease occurs in people aged 30 to 49 years. Women suffer from migraines 2-3 times more often than men. Migraine significantly reduces the ability to work and the quality of life of patients [7]. It was noted that patients with migraine are significantly more likely than in the general population to complain of memory loss [8]. Many researchers point out objective deterioration of cognitive functions in patients with migraine. Other authors, on the contrary, report the absence of objective cognitive impairment in migraines. At the same time, over the past decade, clinical data have been obtained that patients with migraine have an increased risk of stroke, arterial hypertension and diabetes mellitus are more common [9-10]. Interestingly, migraines, as well as ischemic stroke and dementia, are more common in women. In some patients with migraine, magnetic resonance imaging (MRI) reveals areas of damage to the white and, to a lesser extent, gray matter of the brain. The clinical significance of these injuries is debated, and their effect on cognitive functions is unclear.