STUDY OF THYROID FUNCTION IN PREDICTING ARTERIAL HYPERTENSION IN PERIMENOPAUSAL WOMEN

Abstract

Heart disease in women increases significantly perimenopause. Estrogen is believed to have a protective effect on the heart and blood vessels. Its decline during menopause can lead to a variety of changes that increase the risk of developing cardiovascular disease. These include changes in the walls of the blood vessels, making them less elastic, and changes in the lipid profile, such as increases in LDL, the bad cholesterol, and decreases in HDL, the good cholesterol. Arterial hypertension is one of the health problems characterized by high prevalence and high mortality rate. Aging in both men and women is characterized by increases in blood pressure, and the prevalence of hypertension in menopausal women is higher than it is in men, with 41% of menopausal women becoming hypertensive [1]. It has a serious negative effect on the health of women during menopause. Many negative changes, which are thyroid gland dysfunction, decreased insulin resistance, metabolic disorders, occur in the female body due to the decrease in estrogen during menopause. And the changes are the leading cause of cardiovascular disease. The high frequency of arterial hypertension in the female population after perimenopause is due to dyshormonal changes. This review describes possible mechanism of influence of thyroid gland dysfunction on the occurrence of arterial hypertension during perimenopause.