THE ROLE OF CELLULAR IMMUNITY IN OBESITY
Keywords:
Keywords: Obesity, cellular immunity, T lymphocytes, macrophages, chronic inflammation, adipokines, insulin resistance, immunometabolism.Abstract
Abstract. Obesity has become one of the most prevalent non-communicable diseases worldwide and is recognized as a major risk factor for numerous metabolic, cardiovascular, and endocrine disorders. Traditionally considered a consequence of excessive energy intake and reduced physical activity, obesity is now increasingly viewed as a chronic low-grade inflammatory condition characterized by profound alterations in immune system function. In recent years, growing evidence has highlighted the critical role of cellular immunity in the development, progression, and complications of obesity. Understanding the interactions between immune cells and adipose tissue is essential for elucidating the pathogenesis of obesity and identifying novel therapeutic targets.
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