CELLULAR IMMUNITY PARAMETERS IN PATIENTS WITH CORONARY ARTERY DISEASE UNDERGOING CORONARY ARTERY BYPASS GRAFTING

Abstract

Purpose of the study. To determine the prognostic value of cellular immunity parameters in patients with coronary artery disease undergoing coronary artery bypass grafting under cardiopulmonary bypass.

Materials and methods. Patients with coronary artery disease undergoing coronary artery bypass grafting (CABG) under cardiopulmonary bypass were examined in the preoperative and early postoperative periods. Peripheral venous blood samples were collected according to a standardized protocol before surgery and after the intervention. Lymphocyte subpopulations (CD3⁺, CD4⁺, CD8⁺, CD16⁺, CD20⁺) were evaluated in peripheral blood using immunological laboratory methods with monoclonal antibodies. Quantitative assessment of lymphocyte subsets was performed to characterize cellular immunity status. The obtained data were analyzed through dynamic follow-up, comparative evaluation of pre- and postoperative parameters, and statistical analysis using standard variation and correlation methods.