INTEGRATION OF INTENSIVE CARE AND SURGICAL MANAGEMENT IN CHOLANGIOSEPSIS: IMPACT ON CLINICAL OUTCOMES

Abstract

Cholangiosepsis is a severe form of biliary tract infection associated with high morbidity and mortality despite advances in surgical techniques and intensive care medicine. Effective management of this condition requires not only timely surgical source control but also close integration with intensive care support. The aim of this study was to evaluate the impact of coordinated intensive care and surgical management on clinical outcomes in patients with cholangiosepsis. Clinical data from patients treated in a specialized hepatobiliary center were analyzed with particular attention to hemodynamic stabilization, timing of biliary decompression, and multidisciplinary decision-making. The results demonstrate that integrated intensive care and surgical management leads to improved hemodynamic stability, reduced incidence of septic shock and multiple organ dysfunction, lower postoperative complication rates, and decreased mortality. Furthermore, coordinated care was associated with shorter intensive care unit stay and overall hospitalization duration. These findings highlight the critical role of multidisciplinary collaboration in optimizing treatment strategies and improving outcomes in patients with cholangiosepsis.