EARLY DIAGNOSTIC MARKERS AND PROPHYLACTIC INTERVENTIONS TO PREVENT SUPPURATIVE PROGRESSION IN CHILDHOOD HEMATOGENOUS OSTEOMYELITIS
Keywords:
osteomyelitis, children, purulent, MRI, antibiotics, MRSA, preventionAbstract
This study evaluates early diagnostic strategies and targeted prevention of purulent complications in pediatric hematogenous osteomyelitis. A total of 86 children received MRI-supported diagnosis and pathogen-directed antimicrobial therapy, compared with 50 children presenting with purulent complications. Early imaging combined with culture-based treatment significantly reduced abscess formation, transphyseal injury, and surgical need. Oral step-down therapy after clinical and CRP improvement demonstrated high efficacy, while MRSA cases required prolonged intravenous therapy and more frequent surgery. These findings support a multidisciplinary protocol that integrates rapid imaging, targeted antibiotics, and timely surgical decisions to prevent suppurative progression in children with osteomyelitis.
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